National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

B-Cell Activation
Synonyms

B-Cell Activation

Definitions

A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19255

code

C19255

DEFINITION

A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation.

FULL_SYN

B-Cell Activation

label

B-Cell Activation

Legacy Concept Name

B-Cell_Activation

Preferred_Name

B-Cell Activation

prefixIRI

Thesaurus:C19255

Semantic_Type

Cell Function

UMLS_CUI

C1155003

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40833

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