loading...| Preferred Name |
Pancreatic Elastase |
|
| Synonyms |
Chymotrypsin-Like Elastase Pancreatic Elastase 1 Pancreatic Elastase Pancreatic Elastase-1 CELA Family Chymotrypsin-Like Elastase Family CELA |
|
| Definitions |
A family of chymotrypsin-like serine proteinases that specifically hydrolyze amino bonds on the carboxyl side of hydrophobic amino acids, including alanine, leucine, methionine and phenylalanine. These enzymes play roles in digestion and pancreatic regulation of insulin. Elastin is a substrate for some members of the family. Measurement of the concentration of certain pancreatic elastase isoforms in feces can be correlated to the exocrine secretory capacity of the pancreas. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191858 |
|
| code |
C191858 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
A family of chymotrypsin-like serine proteinases that specifically hydrolyze amino bonds on the carboxyl side of hydrophobic amino acids, including alanine, leucine, methionine and phenylalanine. These enzymes play roles in digestion and pancreatic regulation of insulin. Elastin is a substrate for some members of the family. Measurement of the concentration of certain pancreatic elastase isoforms in feces can be correlated to the exocrine secretory capacity of the pancreas. |
|
| DesignNote |
Humans express five pancreatic elastases: CELA1, CELA2A, CELA2B, CELA3A and CELA3B. CELA1 is not expressed by the pancreas. |
|
| Display_Name |
Pancreatic Elastase |
|
| FULL_SYN |
Chymotrypsin-Like Elastase Pancreatic Elastase 1 Pancreatic Elastase Pancreatic Elastase-1 CELA Family Chymotrypsin-Like Elastase Family CELA |
|
| label |
Pancreatic Elastase |
|
| NCI_META_CUI |
CL1905122 |
|
| Preferred_Name |
Pancreatic Elastase |
|
| prefixIRI |
Thesaurus:C191858 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein |
|
| subClassOf |