National Cancer Institute Thesaurus

Last uploaded: February 23, 2024

Preferred Name	Cytotoxic Chemotherapeutic Agent
Synonyms	Cytotoxic Chemotherapy Agent Cytotoxic Chemotherapeutic Agent Antineoplastic Cytotoxic Agent Cytotoxic Antineoplastic Agent
Definitions	Any chemotherapeutic agent that is cytotoxic in nature and non-specifically kills rapidly proliferating cells, including tumor cells. This includes cytotoxic agents that are modified or formulated in such a way as to more specifically target tumor cells but for which the fundamental cytotoxic mechanism of action (MoA) has not changed. Targeted therapy agents that have antineoplastic MoAs are not included.
ID	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186664
code	C186664
DEFINITION	Any chemotherapeutic agent that is cytotoxic in nature and non-specifically kills rapidly proliferating cells, including tumor cells. This includes cytotoxic agents that are modified or formulated in such a way as to more specifically target tumor cells but for which the fundamental cytotoxic mechanism of action (MoA) has not changed. Targeted therapy agents that have antineoplastic MoAs are not included.
FULL_SYN	Cytotoxic Chemotherapy Agent Cytotoxic Chemotherapeutic Agent Antineoplastic Cytotoxic Agent Cytotoxic Antineoplastic Agent
label	Cytotoxic Chemotherapeutic Agent
NCI_META_CUI	CL1779165
Preferred_Name	Cytotoxic Chemotherapeutic Agent
prefixIRI	Thesaurus:C186664
Semantic_Type	Pharmacologic Substance Chemical Viewed Functionally
subClassOf	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C274

Delete	Subject	Author	Type	Created
No notes to display

Delete	Mapping To	Ontology	Source
	http://purl.obolibrary.org/obo/NCIT_C186664	BERO	LOOM