National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ephrin Receptor
Synonyms

Ephrin Receptor

EPH

Definitions

Eph receptor tyrosine kinases and their ligands, the ephrins, appear to lie functionally at the interface between pattern formation and morphogenesis. They play a major role in axonal pathfinding and target recognition during central nervous system (CNS) development. (from Development 1999;126:2033-2044 and Exp Neurol 1999;156:218-22)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18606

code

C18606

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Eph receptor tyrosine kinases and their ligands, the ephrins, appear to lie functionally at the interface between pattern formation and morphogenesis. They play a major role in axonal pathfinding and target recognition during central nervous system (CNS) development. (from Development 1999;126:2033-2044 and Exp Neurol 1999;156:218-22)

DesignNote

The signaling pathways downstream of ephrin receptors are referred to as forward signaling while the signaling pathways downstream of the ephrin ligands are referred to as reverse signaling. (UniProt)

Display_Name

Ephrin Receptor

FULL_SYN

Ephrin Receptor

EPH

label

Ephrin Receptor

Legacy Concept Name

Ephrin_Receptor

Preferred_Name

Ephrin Receptor

prefixIRI

Thesaurus:C18606

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Receptor

UMLS_CUI

C0908506

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20130

Delete Subject Author Type Created
No notes to display