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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18106
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|---|---|
| Preferred Name | Receptor |
| Definitions |
A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.
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| Synonyms |
Receptor Protein
Receptor
receptor
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Receptor
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|---|---|
| Legacy Concept Name |
Receptor
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| Preferred_Name |
Receptor
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
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| prefixIRI |
Thesaurus:C18106
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| DEFINITION |
A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways.
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| UMLS_CUI |
C0597357
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| code |
C18106
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| subClassOf | |
| type | |
| FULL_SYN |
Receptor Protein
Receptor
receptor
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| ALT_DEFINITION |
A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.
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