National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Histologic Grade
Synonyms

histological_grade

Grade (high/low)

Tumor_Grade

Overall Tumor Grade

histological grade

Histologic Grade

Tumor Grade

Histopathologic Grade

Histology Grade

HISTOLOGY_GRADE

Histopathology Grade

Grade

Grading

OVLTGRD

grade

grading

Definitions

The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18000

ALT_DEFINITION

A description of a tumor based on how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread. Grading systems are different for each type of cancer.

An assigned tumor grade based on a defined scoring system.

code

C18000

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159416

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177384

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159417

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C160911

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165451

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186764

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179490

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177396

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157531

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166373

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C166372

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132263

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156953

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132262

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159419

Contributing_Source

CDISC

CPTAC

ICDC

NAACCR

PCDC

DEFINITION

The degree of abnormality of cancer cells, a measure of differentiation, the extent to which cancer cells are similar in appearance and function to healthy cells of the same tissue type. The degree of differentiation often relates to the clinical behavior of the particular tumor. Based on the microscopic findings, tumor grade is commonly described by one of four degrees of severity. Histopathologic grade of a tumor may be used to plan treatment and estimate the future course, outcome, and overall prognosis of disease. Certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast have special grading systems.

FULL_SYN

histological_grade

Grade (high/low)

Tumor_Grade

Overall Tumor Grade

histological grade

Histologic Grade

Tumor Grade

Histopathologic Grade

Histology Grade

HISTOLOGY_GRADE

Histopathology Grade

Grade

Grading

OVLTGRD

grade

grading

Has_PCDC_Data_Type

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25162

Has_PCDC_GCT_Authorized_Value

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28079

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28078

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28077

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43234

Has_PCDC_OS_Authorized_Value

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28079

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28078

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28077

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43234

label

Histologic Grade

Legacy Concept Name

Histopathologic_Grade

Preferred_Name

Histologic Grade

prefixIRI

Thesaurus:C18000

Semantic_Type

Qualitative Concept

UMLS_CUI

C0919553

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28076

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