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National Cancer Institute Thesaurus
Preferred Name | Nicotine Patch | |
Synonyms |
Nicotine Skin Patch Nicotine Transdermal Patch nicotine patch Nicotine Patch NicoDerm CQ |
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Definitions |
A transdermal patch containing the alkaloid nicotine with nicotine replacement activity. Upon administration of the patch, nicotine is slowly released into the bloodstream and, although nicotine binds to nicotinic cholinergic receptors at the autonomic ganglia, adrenal medulla and at neuromuscular junctions as well, the binding of nicotine to the receptors in the central nervous system (CNS) appears to be responsible for the addictive nature of nicotine. Binding to CNS nicotinic acetylcholine receptors causes the release of the neurotransmitter dopamine which appears to be responsible for the addiction of nicotine. Administration of nicotine may prevent nicotine craving and may help with the withdrawal symptoms associated with smoking cessation. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17955 |
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ALT_DEFINITION |
A patch that sticks on the skin and contains a small dose of nicotine, which enters the blood by being absorbed through the skin. This helps stop nicotine cravings and relieves symptoms that occur when a person is trying to quit smoking. A prescription is not needed for nicotine patches.
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code |
C17955
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Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 |
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Contributing_Source |
CTRP
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DEFINITION |
A transdermal patch containing the alkaloid nicotine with nicotine replacement activity. Upon administration of the patch, nicotine is slowly released into the bloodstream and, although nicotine binds to nicotinic cholinergic receptors at the autonomic ganglia, adrenal medulla and at neuromuscular junctions as well, the binding of nicotine to the receptors in the central nervous system (CNS) appears to be responsible for the addictive nature of nicotine. Binding to CNS nicotinic acetylcholine receptors causes the release of the neurotransmitter dopamine which appears to be responsible for the addiction of nicotine. Administration of nicotine may prevent nicotine craving and may help with the withdrawal symptoms associated with smoking cessation.
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Display_Name |
Nicotine Patch
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FULL_SYN |
Nicotine Skin Patch Nicotine Transdermal Patch nicotine patch Nicotine Patch NicoDerm CQ
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label |
Nicotine Patch
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Legacy Concept Name |
Nicotine_Patch
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NCI_Drug_Dictionary_ID |
663019
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PDQ_Closed_Trial_Search_ID |
663019
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PDQ_Open_Trial_Search_ID |
663019
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Preferred_Name |
Nicotine Patch
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prefixIRI |
Thesaurus:C17955
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Semantic_Type |
Pharmacologic Substance
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UMLS_CUI |
C0358855
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subClassOf |
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