National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Nicotine Patch
Synonyms

Nicotine Skin Patch

Nicotine Transdermal Patch

nicotine patch

Nicotine Patch

NicoDerm CQ

Definitions

A transdermal patch containing the alkaloid nicotine with nicotine replacement activity. Upon administration of the patch, nicotine is slowly released into the bloodstream and, although nicotine binds to nicotinic cholinergic receptors at the autonomic ganglia, adrenal medulla and at neuromuscular junctions as well, the binding of nicotine to the receptors in the central nervous system (CNS) appears to be responsible for the addictive nature of nicotine. Binding to CNS nicotinic acetylcholine receptors causes the release of the neurotransmitter dopamine which appears to be responsible for the addiction of nicotine. Administration of nicotine may prevent nicotine craving and may help with the withdrawal symptoms associated with smoking cessation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17955

ALT_DEFINITION

A patch that sticks on the skin and contains a small dose of nicotine, which enters the blood by being absorbed through the skin. This helps stop nicotine cravings and relieves symptoms that occur when a person is trying to quit smoking. A prescription is not needed for nicotine patches.

code

C17955

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

A transdermal patch containing the alkaloid nicotine with nicotine replacement activity. Upon administration of the patch, nicotine is slowly released into the bloodstream and, although nicotine binds to nicotinic cholinergic receptors at the autonomic ganglia, adrenal medulla and at neuromuscular junctions as well, the binding of nicotine to the receptors in the central nervous system (CNS) appears to be responsible for the addictive nature of nicotine. Binding to CNS nicotinic acetylcholine receptors causes the release of the neurotransmitter dopamine which appears to be responsible for the addiction of nicotine. Administration of nicotine may prevent nicotine craving and may help with the withdrawal symptoms associated with smoking cessation.

Display_Name

Nicotine Patch

FULL_SYN

Nicotine Skin Patch

Nicotine Transdermal Patch

nicotine patch

Nicotine Patch

NicoDerm CQ

label

Nicotine Patch

Legacy Concept Name

Nicotine_Patch

NCI_Drug_Dictionary_ID

663019

PDQ_Closed_Trial_Search_ID

663019

PDQ_Open_Trial_Search_ID

663019

Preferred_Name

Nicotine Patch

prefixIRI

Thesaurus:C17955

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0358855

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168699

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