National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Fibroblast Growth Factor Receptor 1
Synonyms

FMS-Like Tyrosine Kinase 2

Fibroblast Growth Factor Receptor 1

Proto-Oncogene c-Fgr

EC 2.7.10.1

CD331 Antigen

Basic Fibroblast Growth Factor Receptor 1

BFGFR

FGFR-1

FGFR1

FLT-2

N-sam

bFGF-R-1

Definitions

Fibroblast growth factor receptor 1 (822 aa, ~92 kDa) is encoded by the human FGFR1 gene. This protein is involved in the regulation of embryonic development, cell proliferation, cell differentiation and cellular migration.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17590

code

C17590

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Fibroblast growth factor receptor 1 (822 aa, ~92 kDa) is encoded by the human FGFR1 gene. This protein is involved in the regulation of embryonic development, cell proliferation, cell differentiation and cellular migration.

DesignNote

At least 21 isoforms of the fibroblast growth factor receptor 1 protein have been described. They are the products of alternative splicing and exibihit tissue-specific patterns of expression.

Display_Name

Fibroblast Growth Factor Receptor 1

FULL_SYN

FMS-Like Tyrosine Kinase 2

Fibroblast Growth Factor Receptor 1

Proto-Oncogene c-Fgr

EC 2.7.10.1

CD331 Antigen

Basic Fibroblast Growth Factor Receptor 1

BFGFR

FGFR-1

FGFR1

FLT-2

N-sam

bFGF-R-1

label

Fibroblast Growth Factor Receptor 1

Legacy Concept Name

Fibroblast_Growth_Factor_Receptor-1

OMIM_Number

136350

Preferred_Name

Fibroblast Growth Factor Receptor 1

prefixIRI

Thesaurus:C17590

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Receptor

Swiss_Prot

P11362

UMLS_CUI

C1527757

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17297

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