loading...| Preferred Name | Mitogen-Activated Protein Kinase 1 | |
| Synonyms |
MAP Kinase 1 MAP Kinase 2 MAP Kinase Isoform p42 Mitogen-Activated Protein Kinase 1 Extracellular Signal-Regulated Kinase 2 Mitogen-Activated Protein Kinase 2 EC 2.7.11.24 ERK-2 ERT1 MAPK 1 MAPK 2 MAPK1 PRKM1 p42-MAPK p42MAPK |
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| Definitions |
Mitogen-activated protein kinase 1 (390 aa, ~41 kDa) is encoded by the human MAPK1 gene. This protein plays a role in cell cycle regulation, signal transduction, transcriptional regulation and serine/threonine phosphorylation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17589 |
|
| code |
C17589 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Mitogen-activated protein kinase 1 (390 aa, ~41 kDa) is encoded by the human MAPK1 gene. This protein plays a role in cell cycle regulation, signal transduction, transcriptional regulation and serine/threonine phosphorylation. |
|
| DesignNote |
When MAPK1 is autophosphorylated or phosphorylated/activated by upstream kinases on threonine and tyrosine residues, it forms dimers with phosphorylated and unphosphorylated ERK partners, translocates to the nucleus and phosphorylates target transcription factors. |
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| Display_Name |
Mitogen-Activated Protein Kinase 1 |
|
| FULL_SYN |
MAP Kinase 1 MAP Kinase 2 MAP Kinase Isoform p42 Mitogen-Activated Protein Kinase 1 Extracellular Signal-Regulated Kinase 2 Mitogen-Activated Protein Kinase 2 EC 2.7.11.24 ERK-2 ERT1 MAPK 1 MAPK 2 MAPK1 PRKM1 p42-MAPK p42MAPK |
|
| label |
Mitogen-Activated Protein Kinase 1 |
|
| Legacy Concept Name |
Mitogen-Activated_Protein_Kinase-1 |
|
| OMIM_Number |
176948 |
|
| Preferred_Name |
Mitogen-Activated Protein Kinase 1 |
|
| prefixIRI |
Thesaurus:C17589 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
|
| Swiss_Prot |
P28482 |
|
| UMLS_CUI |
C2713871 |
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| subClassOf |