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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17561
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17561
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|---|---|
| Preferred Name | Fusion Protein |
| Definitions |
A protein in which the coding region of two genes have become in-frame and co-continuous. Fusion proteins can be formed by chromosomal breakage and/or recombination and also can be experimentally created using recombinant DNA techniques.
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| Synonyms |
Fusion Protein
Chimeric Protein
fusion protein
Chimera Protein
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Fusion Protein
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|---|---|
| Legacy Concept Name |
Fusion_Protein
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| Preferred_Name |
Fusion Protein
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| Semantic_Type |
Amino Acid, Peptide, or Protein
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| prefixIRI |
Thesaurus:C17561
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| DEFINITION |
A protein in which the coding region of two genes have become in-frame and co-continuous. Fusion proteins can be formed by chromosomal breakage and/or recombination and also can be experimentally created using recombinant DNA techniques.
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| UMLS_CUI |
C0162768
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| code |
C17561
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| subClassOf | |
| type | |
| FULL_SYN |
Fusion Protein
Chimeric Protein
fusion protein
Chimera Protein
|
| ALT_DEFINITION |
A protein made from a fusion gene, which is created by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.
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