National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Fusion Protein
Synonyms

Fusion Protein

Chimeric Protein

fusion protein

Chimera Protein

Definitions

A protein in which the coding region of two genes have become in-frame and co-continuous. Fusion proteins can be formed by chromosomal breakage and/or recombination and also can be experimentally created using recombinant DNA techniques.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17561

ALT_DEFINITION

A protein made from a fusion gene, which is created by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.

code

C17561

DEFINITION

A protein in which the coding region of two genes have become in-frame and co-continuous. Fusion proteins can be formed by chromosomal breakage and/or recombination and also can be experimentally created using recombinant DNA techniques.

FULL_SYN

Fusion Protein

Chimeric Protein

fusion protein

Chimera Protein

label

Fusion Protein

Legacy Concept Name

Fusion_Protein

Preferred_Name

Fusion Protein

prefixIRI

Thesaurus:C17561

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0162768

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20032

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