National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Breakpoint Cluster Region Protein
Synonyms

BCR Protein

Renal Carcinoma Antigen NY-REN-26

Breakpoint Cluster Region Protein

EC 2.7.11.1

ALL

BCR

BCR1

CML

D22S11

D22S662

PHL

Definitions

Breakpoint cluster region protein (1271 aa, ~143 kDa) is encoded by the human BCR gene. This protein is involved in both serine/threonine-protein kinase and GTPase-activating protein activities.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17477

code

C17477

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Breakpoint cluster region protein (1271 aa, ~143 kDa) is encoded by the human BCR gene. This protein is involved in both serine/threonine-protein kinase and GTPase-activating protein activities.

DesignNote

Breakpoint cluster region protein is a GTPase-activating protein for the small GTPases Ras-related C3 botulinum toxin substrate 1 and cell division control protein 42 homolog. (UniProt)

Display_Name

Breakpoint Cluster Region Protein

FULL_SYN

BCR Protein

Renal Carcinoma Antigen NY-REN-26

Breakpoint Cluster Region Protein

EC 2.7.11.1

ALL

BCR

BCR1

CML

D22S11

D22S662

PHL

label

Breakpoint Cluster Region Protein

Legacy Concept Name

BCR_Protein

OMIM_Number

151410

Preferred_Name

Breakpoint Cluster Region Protein

prefixIRI

Thesaurus:C17477

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

P11274

UMLS_CUI

C0105421

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17325

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17298

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17494

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