loading...| Preferred Name |
Telomerase |
|
| Synonyms |
Telomerase telomerase |
|
| Definitions |
A reverse transcriptase responsible for maintaining the telomere length of replicating cells. Telomerase recognizes a telomere-specific GC rich sequence and adds telomeric repeats by using and RNA template. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17470 |
|
| ALT_DEFINITION |
An enzyme in cells that helps keep them alive by adding DNA to telomeres (the ends of chromosomes). Each time a cell divides, the telomeres lose a small amount of DNA and become shorter. Over time, the chromosomes become damaged and the cells die. Telomerase helps keep this from happening. Cancer cells usually have more telomerase than most normal cells. |
|
| code |
C17470 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
A reverse transcriptase responsible for maintaining the telomere length of replicating cells. Telomerase recognizes a telomere-specific GC rich sequence and adds telomeric repeats by using and RNA template. |
|
| Display_Name |
Telomerase |
|
| FULL_SYN |
Telomerase telomerase |
|
| label |
Telomerase |
|
| Legacy Concept Name |
Telomerase |
|
| Preferred_Name |
Telomerase |
|
| prefixIRI |
Thesaurus:C17470 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
|
| UMLS_CUI |
C0087071 |
|
| subClassOf |