National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Glucose-6-Phosphate Isomerase

Synonyms

Glucosephosphate Isomerase

Phosphosaccharomutase

Sperm Antigen-36

Glucose-6-Phosphate Isomerase

Hexose Monophosphate Isomerase

Glucose Phosphate Isomerase

Autocrine Motility Factor

Hexosephosphate Isomerase

Neuroleukin

Phosphohexomutase

Sperm Antigen 36

Phosphohexose Isomerase

Phosphoglucose Isomerase

Oxoisomerase

D-Glucose-6-Phosphate Ketol-Isomerase

AMF

EC 5.3.1.9

GPI

NLK

PGI

PHI

SA-36

Definitions

Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a cytoplasmic homodimer and has a secreted monomeric form that either exhibits cytokine activity or can function as a neurotrophic factor.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17428

code

C17428

DEFINITION

Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a cytoplasmic homodimer and has a secreted monomeric form that either exhibits cytokine activity or can function as a neurotrophic factor.

DesignNote

The enzymatically active form of glucose-6-phosphate isomerase (GPI) is a cytosolic homodimer. GPI expresses cytokine activity when secreted as a monomer. (UniProt)

FULL_SYN

Glucosephosphate Isomerase

Phosphosaccharomutase

Sperm Antigen-36

Glucose-6-Phosphate Isomerase

Hexose Monophosphate Isomerase

Glucose Phosphate Isomerase

Autocrine Motility Factor

Hexosephosphate Isomerase

Neuroleukin

Phosphohexomutase

Sperm Antigen 36

Phosphohexose Isomerase

Phosphoglucose Isomerase

Oxoisomerase

D-Glucose-6-Phosphate Ketol-Isomerase

AMF

EC 5.3.1.9

GPI

NLK

PGI

PHI

SA-36

label

Glucose-6-Phosphate Isomerase

Legacy Concept Name

Glucose_Phosphate_Isomerase

OMIM_Number

172400

Preferred_Name

Glucose-6-Phosphate Isomerase

prefixIRI

Thesaurus:C17428

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

P06744

UMLS_CUI

C0085144

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16759

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