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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17411
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17411
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|---|---|
| Preferred Name | Fibroblast Growth Factor Receptor 2 |
| Definitions |
Fibroblast growth factor receptor 2 (821 aa, ~92 kDa) is encoded by the human FGFR2 gene. This protein plays a role in heparin-dependent fibroblast growth factor signaling.
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| Synonyms |
CD332 Antigen
Fibroblast Growth Factor Receptor 2
Fibroblast Growth Factor Receptor 2 Isoform IIIc
FGFR-2 IIIc
EC 2.7.10.1
FGFR2(IIIc)
Keratinocyte Growth Factor Receptor
KGF Receptor
BEK
FGFR-2
FGFR2
FGFR2 IIIc
FGFR2-IIIc
FGFR2IIIc
K-sam
KGFR
See more
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Fibroblast Growth Factor Receptor 2
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|---|---|
| Legacy Concept Name |
Fibroblast_Growth_Factor_Receptor-2
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| DesignNote |
At least 23 isoforms of the fibroblast growth factor receptor 2 protein have been described. They are the products of alternative splicing and exibihit tissue-specific patterns of expression.
UniProt has designated this isoform of fibroblast growth factor receptor 2, where alternative splicing leads the expression of the IIIc exon encoding the second half of the third immunoglobulin-like domain located in the extracellular domain of this receptor, as the canonical form. This isoform is expressed in mesenchymal lineage cells and has differential ligand binding activity when compared to the IIIa and IIIb forms.
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| Preferred_Name |
Fibroblast Growth Factor Receptor 2
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| Display_Name |
Fibroblast Growth Factor Receptor 2
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| OMIM_Number |
176943
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
Receptor
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| prefixIRI |
Thesaurus:C17411
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| DEFINITION |
Fibroblast growth factor receptor 2 (821 aa, ~92 kDa) is encoded by the human FGFR2 gene. This protein plays a role in heparin-dependent fibroblast growth factor signaling.
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| UMLS_CUI |
C1259992
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| code |
C17411
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| Swiss_Prot |
P21802
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| subClassOf | |
| type | |
| FULL_SYN |
CD332 Antigen
Fibroblast Growth Factor Receptor 2
Fibroblast Growth Factor Receptor 2 Isoform IIIc
FGFR-2 IIIc
EC 2.7.10.1
FGFR2(IIIc)
Keratinocyte Growth Factor Receptor
KGF Receptor
BEK
FGFR-2
FGFR2
FGFR2 IIIc
FGFR2-IIIc
FGFR2IIIc
K-sam
KGFR
See more
See less
|
| Contributing_Source |
CTRP
|
| Concept_In_Subset |
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