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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1736
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1736
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|---|---|
| Preferred Name | Aminobenzoate Potassium |
| Definitions |
The potassium salt form of aminobenzoate, with anti-inflammatory and antifibrotic activities. Aminobenzoate potassium increases oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity, which requires oxygen as a substrate. Enhanced MAO activity maybe accountable for the prevention or regression of fibrosis, which may occur due to too much serotonin or too little MAO activity.
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| Synonyms |
AMINOBENZOATE POTASSIUM
Aminobenzoate Potassium
Potassium para-Aminobenzoate
Potassium p-Aminobenzoate
Potaba
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Aminobenzoate Potassium
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|---|---|
| Accepted_Therapeutic_Use_For |
Diseases involving fibrosis and nonsuppurative inflammation
|
| Legacy Concept Name |
Aminobenzoate_Potassium
|
| NCI_Drug_Dictionary_ID |
39571
|
| PDQ_Closed_Trial_Search_ID |
39571
|
| Preferred_Name |
Aminobenzoate Potassium
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| prefixIRI |
Thesaurus:C1736
|
| DEFINITION |
The potassium salt form of aminobenzoate, with anti-inflammatory and antifibrotic activities. Aminobenzoate potassium increases oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity, which requires oxygen as a substrate. Enhanced MAO activity maybe accountable for the prevention or regression of fibrosis, which may occur due to too much serotonin or too little MAO activity.
|
| UMLS_CUI |
C0543464
|
| code |
C1736
|
| Chemical_Formula |
C7H6NO2.K
|
| subClassOf | |
| type | |
| CAS_Registry |
138-84-1
|
| FULL_SYN |
AMINOBENZOATE POTASSIUM
Aminobenzoate Potassium
Potassium para-Aminobenzoate
Potassium p-Aminobenzoate
Potaba
|
| FDA_UNII_Code |
41KZS5432U
|
| PDQ_Open_Trial_Search_ID |
39571
|
| Contributing_Source |
FDA
|
| Concept_In_Subset | |
| Has_Free_Acid_Or_Base_Form |
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