loading...| Preferred Name |
Mast/Stem Cell Growth Factor Receptor Kit |
|
| Synonyms |
Proto-Oncogene Tyrosine-Protein Kinase Kit KIT (CD117) Stem Cell Factor Receptor Tyrosine-Protein Kinase Kit stem cell factor receptor Mast/Stem Cell Growth Factor Receptor Kit Mast Cell Growth Factor Receptor c-kit receptor EC 2.7.10.1 Piebald Trait Protein Proto-Oncogene c-Kit v-kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog SCF Receptor Antigen CD117 CD117 Antigen C-KIT CD117 KIT PBT SCFR p145 c-kit |
|
| Definitions |
Mast/stem cell growth factor receptor Kit (976 aa, ~110 kDa) is encoded by the human KIT gene. This protein is involved in cell survival, tyrosine phosphorylation and ligand-mediated signaling. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17328 |
|
| ALT_DEFINITION |
A protein on the surface of some cells that binds to biologic substance called stem cell factor (SCF). SCF causes certain types of blood cells to grow. The stem cell factor receptor is found at high levels or in a changed form on some types of cancer cells. This may cause these cells to grow rapidly when SCF is present. The stem cell factor receptor is a type of receptor tyrosine kinase. |
|
| code |
C17328 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159414 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CPTAC CTRP GDC |
|
| DEFINITION |
Mast/stem cell growth factor receptor Kit (976 aa, ~110 kDa) is encoded by the human KIT gene. This protein is involved in cell survival, tyrosine phosphorylation and ligand-mediated signaling. |
|
| Display_Name |
Mast/Stem Cell Growth Factor Receptor Kit |
|
| FULL_SYN |
Proto-Oncogene Tyrosine-Protein Kinase Kit KIT (CD117) Stem Cell Factor Receptor Tyrosine-Protein Kinase Kit stem cell factor receptor Mast/Stem Cell Growth Factor Receptor Kit Mast Cell Growth Factor Receptor c-kit receptor EC 2.7.10.1 Piebald Trait Protein Proto-Oncogene c-Kit v-kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog SCF Receptor Antigen CD117 CD117 Antigen C-KIT CD117 KIT PBT SCFR p145 c-kit |
|
| Is_Value_For_GDC_Property | ||
| label |
Mast/Stem Cell Growth Factor Receptor Kit |
|
| Legacy Concept Name |
Stem_Cell_Factor_Receptor |
|
| Maps_To |
CD117 |
|
| NCI_META_CUI |
CL964236 |
|
| OMIM_Number |
164920 |
|
| Preferred_Name |
Mast/Stem Cell Growth Factor Receptor Kit |
|
| prefixIRI |
Thesaurus:C17328 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme Receptor |
|
| Swiss_Prot |
P10721 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/SNOMEDCT/103165007 | SNOMEDCT | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C17328 | BERO | LOOM | |
| http://www.drugtargetontology.org/dto/DTO_03100231 | DTO | LOOM |