National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Innate Lymphoid Cell
Synonyms

Innate Lymphoid Cell

ILC

Definitions

Innate immune cells in the lymphoid lineage that do not express recombination-activating genes (RAGs), T-cell or B-cell receptors, or any myeloid or dendritic cell markers. There are several subtypes of innate lymphoid cells (ILC): group 1 ILC express TBX21 and Th1 cytokines, group 2 ILC produce type 2 cytokines, group 3 ILC produce interleukin-17A (IL-17A) and/or IL-22 and lymphoid tissue inducer cells (LTi cells) do not express CD3 but do express IL-7, CD45, CD4 and a large number of additional markers.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171057

code

C171057

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Innate immune cells in the lymphoid lineage that do not express recombination-activating genes (RAGs), T-cell or B-cell receptors, or any myeloid or dendritic cell markers. There are several subtypes of innate lymphoid cells (ILC): group 1 ILC express TBX21 and Th1 cytokines, group 2 ILC produce type 2 cytokines, group 3 ILC produce interleukin-17A (IL-17A) and/or IL-22 and lymphoid tissue inducer cells (LTi cells) do not express CD3 but do express IL-7, CD45, CD4 and a large number of additional markers.

Display_Name

Innate Lymphoid Cell

FULL_SYN

Innate Lymphoid Cell

ILC

label

Innate Lymphoid Cell

NCI_META_CUI

CL1405432

Preferred_Name

Innate Lymphoid Cell

prefixIRI

Thesaurus:C171057

Semantic_Type

Cell

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C132890

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