loading...| Preferred Name |
Proto-Oncogene |
|
| Synonyms |
Proto-Oncogene Cellular Oncogenes proto-oncogene Cellular Oncogene c-ONC |
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| Definitions |
Oncogenes are altered forms of normal cellular genes called proto-oncogene. Many proto-oncogenes are homologous to viral oncogenes and involved in the control of cell proliferation or differentiation. Mutations, amplifications or rearrangements of proto-oncogenes lead to upregulated or deregulated cell growth and allow them to function as oncogenes. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17023 |
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| ALT_DEFINITION |
A gene involved in normal cell growth. Mutations (changes) in a proto-oncogene may cause it to become an oncogene, which can cause the growth of cancer cells. |
|
| code |
C17023 |
|
| DEFINITION |
Oncogenes are altered forms of normal cellular genes called proto-oncogene. Many proto-oncogenes are homologous to viral oncogenes and involved in the control of cell proliferation or differentiation. Mutations, amplifications or rearrangements of proto-oncogenes lead to upregulated or deregulated cell growth and allow them to function as oncogenes. |
|
| FULL_SYN |
Proto-Oncogene Cellular Oncogenes proto-oncogene Cellular Oncogene c-ONC |
|
| label |
Proto-Oncogene |
|
| Legacy Concept Name |
Proto-Oncogene |
|
| Preferred_Name |
Proto-Oncogene |
|
| prefixIRI |
Thesaurus:C17023 |
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| Semantic_Type |
Classification |
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| UMLS_CUI |
C0033713 |
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| subClassOf |