loading...| Preferred Name |
Ibuprofen Sodium |
|
| Synonyms |
Ibuprofen Sodium IBUPROFEN SODIUM |
|
| Definitions |
The sodium salt form of ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Upon administration, ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170048 |
|
| CAS_Registry |
527688-20-6 |
|
| code |
C170048 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 |
|
| Contributing_Source |
FDA |
|
| DEFINITION |
The sodium salt form of ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Upon administration, ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
|
| FDA_UNII_Code |
RM1CE97Z4N |
|
| FULL_SYN |
Ibuprofen Sodium IBUPROFEN SODIUM |
|
| label |
Ibuprofen Sodium |
|
| NCI_META_CUI |
CL1382278 |
|
| Preferred_Name |
Ibuprofen Sodium |
|
| prefixIRI |
Thesaurus:C170048 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/SNOMEDCT/725863000 | SNOMEDCT | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C170048 | BERO | LOOM | |
| http://purl.bioontology.org/ontology/NDDF/006088 | NDDF | LOOM |