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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Histone H2A | |
| Synonyms |
HISTONE H2A Histone H2A H2A HIST1H2A Histone 2A |
|
| Definitions |
Slightly lysine rich histone. One of four histones assembled into a nucleosomal core octamer. Various posttranslationally modified forms and variants exist. Combines with histone H2B in a heterodimer; two H2A/H2B dimers are incorporated in the nucleosomal octamer. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16684 |
|
| ALT_DEFINITION |
An antigen in the core histone family and a subunit of the nucleosome complex, with a designation of H2A. It can be considered as an autoantigen and is commonly associated with the autoimmune diseases systemic lupus erythematosus and rheumatoid arthritis.
|
|
| code |
C16684
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CDISC CTRP GDC
|
|
| DEFINITION |
Slightly lysine rich histone. One of four histones assembled into a nucleosomal core octamer. Various posttranslationally modified forms and variants exist. Combines with histone H2B in a heterodimer; two H2A/H2B dimers are incorporated in the nucleosomal octamer.
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|
| Display_Name |
Histone H2A
|
|
| FULL_SYN |
HISTONE H2A Histone H2A H2A HIST1H2A Histone 2A
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| Is_Value_For_GDC_Property | ||
| label |
Histone H2A
|
|
| Legacy Concept Name |
Histone-H2A
|
|
| Maps_To |
H2A
|
|
| Preferred_Name |
Histone H2A
|
|
| prefixIRI |
Thesaurus:C16684
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|
| Semantic_Type |
Amino Acid, Peptide, or Protein
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|
| UMLS_CUI |
C0019646
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|
| subClassOf |
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