National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16615
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16615
Preferred Name

Homeobox Gene

Definitions
A family of genes that contain a highly conserved sequence of approximately 180 nucleotides, which encode an approximately 60 amino acid helix-turn-helix DNA binding domain made up of 2 antiparallel alpha helices and one nearly perpendicular alpha helix connected by short chains of unstructured amino acid sequences. This gene family is involved in transcriptional regulation during embryonic development.
Synonyms
Homeodomain Gene
Homeobox Family Gene
Homeobox Gene
Hox Gene
Type http://www.w3.org/2002/07/owl#Class
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