National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Homeobox Gene

Synonyms

Homeodomain Gene

Homeobox Family Gene

Homeobox Gene

Hox Gene

Definitions

A family of genes that contain a highly conserved sequence of approximately 180 nucleotides, which encode an approximately 60 amino acid helix-turn-helix DNA binding domain made up of 2 antiparallel alpha helices and one nearly perpendicular alpha helix connected by short chains of unstructured amino acid sequences. This gene family is involved in transcriptional regulation during embryonic development.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16615

code

C16615

DEFINITION

A family of genes that contain a highly conserved sequence of approximately 180 nucleotides, which encode an approximately 60 amino acid helix-turn-helix DNA binding domain made up of 2 antiparallel alpha helices and one nearly perpendicular alpha helix connected by short chains of unstructured amino acid sequences. This gene family is involved in transcriptional regulation during embryonic development.

FULL_SYN

Homeodomain Gene

Homeobox Family Gene

Homeobox Gene

Hox Gene

Gene_Encodes_Product

Homeobox Protein

label

Homeobox Gene

Legacy Concept Name

Homeobox_Gene

Preferred_Name

Homeobox Gene

prefixIRI

Thesaurus:C16615

Semantic_Type

Gene or Genome

UMLS_CUI

C0017347

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20420

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