National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Gene Amplification

Synonyms

Transcript Amplification

gene amplification

Amplification

Gene Amplification

Definitions

Any DNA sequence rearrangement that results in the gain of one or more copies of a DNA segment that contains at least one gene.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16605

ALT_DEFINITION

An increase in the number of copies of a gene. There may also be an increase in the RNA and protein made from that gene. Gene amplification is common in cancer cells, and some amplified genes may cause cancer cells to grow or become resistant to anticancer drugs. Genes may also be amplified in the laboratory for research purposes.

code

C16605

DEFINITION

Any DNA sequence rearrangement that results in the gain of one or more copies of a DNA segment that contains at least one gene.

FULL_SYN

Transcript Amplification

gene amplification

Amplification

Gene Amplification

label

Gene Amplification

Legacy Concept Name

Gene_Amplification

Preferred_Name

Gene Amplification

prefixIRI

Thesaurus:C16605

Semantic_Type

Genetic Function

UMLS_CUI

C0017256

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16607

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