National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Coagulation Factor VII

Synonyms

Coagulation Factor VII

Proconvertin

EC 3.4.21.21

Serum Prothrombin Conversion Accelerator

F7

Factor VII

Definitions

Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16570

code

C16570

DEFINITION

Coagulation factor VII (466 aa, ~52 kDa) is encoded by the human F7 gene. This protein is involved in both binding to tissue factor and the initiation of blood coagulation.

DesignNote

Coagulation factor VII is converted from a zymogen to an active protease through a single proteolytic cleavage by by factor Xa, factor XIIa, factor IXa, or thrombin. (UniProt)

FULL_SYN

Coagulation Factor VII

Proconvertin

EC 3.4.21.21

Serum Prothrombin Conversion Accelerator

F7

Factor VII

label

Coagulation Factor VII

Legacy Concept Name

Coagulation_Factor-VII

OMIM_Number

613878

Preferred_Name

Coagulation Factor VII

prefixIRI

Thesaurus:C16570

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

P08709

UMLS_CUI

C0015502

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16354

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17123

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