loading...| Preferred Name | HMG-CoA Reductase Inhibitor | |
| Synonyms |
Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors hydroxymethylglutaryl-coenzyme A reductase inhibitor HMG-CoA reductase inhibitor HMG-CoA Reductase Inhibitor Statin statin |
|
| Definitions |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1655 |
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| ALT_DEFINITION |
Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer. An HMG-CoA reductase inhibitor ("statin"). Lipid-lowering medications with proven ASCVD benefits. |
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| CHEBI_ID |
CHEBI:35664 |
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| code |
C1655 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387 |
|
| Contributing_Source |
ACC/AHA GDC |
|
| DEFINITION |
Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels. |
|
| FULL_SYN |
Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors hydroxymethylglutaryl-coenzyme A reductase inhibitor HMG-CoA reductase inhibitor HMG-CoA Reductase Inhibitor Statin statin |
|
| Has_ACC-AHA_SARS2_Authorized_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 |
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| Is_Value_For_GDC_Property | ||
| label |
HMG-CoA Reductase Inhibitor |
|
| Legacy Concept Name |
HMG-CoA_Reductase_Inhibitor |
|
| Maps_To |
Statin, NOS |
|
| Preferred_Name |
HMG-CoA Reductase Inhibitor |
|
| prefixIRI |
Thesaurus:C1655 |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C0360714 |
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| subClassOf |