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National Cancer Institute Thesaurus
Last uploaded:
July 2, 2026
| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1651
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1651
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|---|---|
| Preferred Name | Motexafin Lutetium |
| Definitions |
A pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects. (NCI04)
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| Synonyms |
lutetium texaphyrin
Lutetium Texaphyrin
Lutetium texaphyrin
motexafin lutetium
Motexafin Lutetium
MOTEXAFIN LUTETIUM
Lutetium Texaphrin
Antrin
Lu tex
Lu-Tex
Lutex
Lutrin
Optrin
PCI-0123
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label | Motexafin Lutetium
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|---|---|
| prefixIRI | Thesaurus:C1651
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| code | C1651
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| DEFINITION | A pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects. (NCI04)
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| ALT_DEFINITION | A substance that is being studied in the treatment of cancer using photodynamic therapy. It belongs to the family of drugs called metallotexaphyrins.
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| Is_Value_For_GDC_Property | |
| Legacy Concept Name | Motexafin_Lutetium
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| PDQ_Open_Trial_Search_ID | 42402
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| Contributing_Source |
CTRP
FDA
GDC
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| NCI_Drug_Dictionary_ID | 42402
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| FULL_SYN |
lutetium texaphyrin
Lutetium Texaphyrin
Lutetium texaphyrin
motexafin lutetium
Motexafin Lutetium
MOTEXAFIN LUTETIUM
Lutetium Texaphrin
Antrin
Lu tex
Lu-Tex
Lutex
Lutrin
Optrin
PCI-0123
See more
See less
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| Chemical_Formula | C48H66N5O10.2C2H3O2.Lu.H2O
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| UMLS_CUI | C0338310
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| Maps_To | Motexafin Lutetium
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| FDA_UNII_Code | 0A85BJ22L6
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| NSC Number | 695239
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| Preferred_Name | Motexafin Lutetium
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| type | |
| subClassOf | |
| Display_Name | Motexafin Lutetium
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| PDQ_Closed_Trial_Search_ID | 42402
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| CAS_Registry | 156436-90-7
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| Concept_In_Subset |
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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