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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Ribozyme | |
| Synonyms |
RNA, Catalytic Catalytic RNA Ribonucleic Enzyme RIBOZYME Ribozyme |
|
| Definitions |
RNA that contains an intron sequence which has an enzyme-like catalytic activity. This intron sequence has been shown to fold up to form a complex surface that can function like an enzyme in reactions with other RNA molecules and thus synthesize new molecules even in the absence of protein. Synthetic ribozymes can be engineered to specifically cleave a target RNA sequence causing expression down regulation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1292 |
|
| ALT_DEFINITION |
RNA that contains an intron sequence which has an enzyme-like catalytic activity. This intron sequence can function like an enzyme in reactions with other RNA molecules and thus synthesize new molecules even in the absence of protein.
|
|
| code |
C1292
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830 |
|
| Contributing_Source |
CDISC
|
|
| DEFINITION |
RNA that contains an intron sequence which has an enzyme-like catalytic activity. This intron sequence has been shown to fold up to form a complex surface that can function like an enzyme in reactions with other RNA molecules and thus synthesize new molecules even in the absence of protein. Synthetic ribozymes can be engineered to specifically cleave a target RNA sequence causing expression down regulation.
|
|
| FULL_SYN |
RNA, Catalytic Catalytic RNA Ribonucleic Enzyme RIBOZYME Ribozyme
|
|
| label |
Ribozyme
|
|
| Legacy Concept Name |
Ribozyme
|
|
| Preferred_Name |
Ribozyme
|
|
| prefixIRI |
Thesaurus:C1292
|
|
| Semantic_Type |
Nucleic Acid, Nucleoside, or Nucleotide Enzyme
|
|
| UMLS_CUI |
C0080125
|
|
| subClassOf |
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