National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1292
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1292
Preferred Name

Ribozyme

Definitions
RNA that contains an intron sequence which has an enzyme-like catalytic activity. This intron sequence has been shown to fold up to form a complex surface that can function like an enzyme in reactions with other RNA molecules and thus synthesize new molecules even in the absence of protein. Synthetic ribozymes can be engineered to specifically cleave a target RNA sequence causing expression down regulation.
Synonyms
RNA, Catalytic
Catalytic RNA
Ribonucleic Enzyme
RIBOZYME
Ribozyme
Type http://www.w3.org/2002/07/owl#Class
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