National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Interferon Regulatory Factor 7

Synonyms

Interferon Regulatory Factor 7

Interferon Regulatory Factor-7

IRF-7

IRF7

Definitions

Interferon regulatory factor 7 (503 aa, ~54 kDa) is encoded by the human IRF7 gene. This protein plays a role in the cellular response to viral infection.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128883

code

C128883

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177415

Contributing_Source

CTRP

DEFINITION

Interferon regulatory factor 7 (503 aa, ~54 kDa) is encoded by the human IRF7 gene. This protein plays a role in the cellular response to viral infection.

DesignNote

Interferon regulatory factor 7 has at least 4 isoforms produced by alternative splicing, called IRF7A, IRF7B (beta), IRF7C (gamma) and IRF7H. UniProt considers IRF7A the canonical form. IRF7B and IRF7C are C-terminally truncated variants of IRF7A. IRF7H has a unique N-terminal domain.

Display_Name

Interferon Regulatory Factor 7

FULL_SYN

Interferon Regulatory Factor 7

Interferon Regulatory Factor-7

IRF-7

IRF7

label

Interferon Regulatory Factor 7

OMIM_Number

605047

Preferred_Name

Interferon Regulatory Factor 7

prefixIRI

Thesaurus:C128883

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

Q92985

UMLS_CUI

C1530281

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17207

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