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National Cancer Institute Thesaurus
| Preferred Name | Recombinant Granulocyte-Macrophage Colony-Stimulating Factor | |
| Synonyms |
Recombinant Granulocyte-Macrophage Colony-Stimulating Factor Recombinanr Colony-Stimulating Factor 2 Colony-Stimulating Factor, Granulocyte-Macrophage CSF 39300/GM-CSF GM-CSF (Schering) CSF-GM (Hoechst) Recombinant Colony-Stimulating Factor 2 CSF 39300 GM CSF GM-CSF GMCSF |
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| Definitions |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein cytokine growth factor granulocyte-macrophage colony stimulating factor (GM-CSF). Therapeutic GM-CSF induces the clonal expansion and differentiation of progenitor blood cells and stimulates the cytotoxicity of monocytes and neutrophils, thereby restoring immune function and host antitumor immune responses and stimulating engraftment of transplanted bone marrow tissue. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1288 |
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| CAS_Registry |
83869-56-1
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| code |
C1288
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 |
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| Contributing_Source |
GDC
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| DEFINITION |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein cytokine growth factor granulocyte-macrophage colony stimulating factor (GM-CSF). Therapeutic GM-CSF induces the clonal expansion and differentiation of progenitor blood cells and stimulates the cytotoxicity of monocytes and neutrophils, thereby restoring immune function and host antitumor immune responses and stimulating engraftment of transplanted bone marrow tissue. (NCI04)
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| FULL_SYN |
Recombinant Granulocyte-Macrophage Colony-Stimulating Factor Recombinanr Colony-Stimulating Factor 2 Colony-Stimulating Factor, Granulocyte-Macrophage CSF 39300/GM-CSF GM-CSF (Schering) CSF-GM (Hoechst) Recombinant Colony-Stimulating Factor 2 CSF 39300 GM CSF GM-CSF GMCSF
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| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
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|
| Legacy Concept Name |
Therapeutic_Granulocyte-Macrophage_Colony-Stimulating_Factor
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|
| Maps_To |
Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
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| NSC Number |
613795 617589 622183 643496
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|
| Preferred_Name |
Recombinant Granulocyte-Macrophage Colony-Stimulating Factor
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|
| prefixIRI |
Thesaurus:C1288
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance
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| UMLS_CUI |
C0376563
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| subClassOf |
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