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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Recombinant Granulocyte Colony-Stimulating Factor | |
| Synonyms |
Recombinant Colony-Stimulating Factor 3 Recombinant Granulocyte Colony-Stimulating Factor rhG-CSF |
|
| Definitions |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1287 |
|
| Accepted_Therapeutic_Use_For |
Neutropenia
|
|
| CAS_Registry |
143011-72-7
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|
| code |
C1287
|
|
| Concept_In_Subset | ||
| DEFINITION |
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)
|
|
| FULL_SYN |
Recombinant Colony-Stimulating Factor 3 Recombinant Granulocyte Colony-Stimulating Factor rhG-CSF
|
|
| label |
Recombinant Granulocyte Colony-Stimulating Factor
|
|
| Legacy Concept Name |
Recombinant_Granulocyte_Colony_Stimulating_Factor
|
|
| NCI_Drug_Dictionary_ID |
618712
|
|
| PDQ_Closed_Trial_Search_ID |
618712
|
|
| PDQ_Open_Trial_Search_ID |
618712
|
|
| Preferred_Name |
Recombinant Granulocyte Colony-Stimulating Factor
|
|
| prefixIRI |
Thesaurus:C1287
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|
| Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor
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|
| UMLS_CUI |
C0376562
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|
| subClassOf |
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