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National Cancer Institute Thesaurus
| Preferred Name | 5-Hydroxylysine | |
| Synonyms |
5-Hydroxy-Lysine (2S,5R)-5-Hydroxylysine L-Hydroxylysine Hydroxylysine HYDROXYLYSINE (2S,5R)-2,6-Diamino-5-Hydroxyhexanoic Acid (2S,5R)-2,6-Diamino-5-Hydroxyhexanoate Erythro-5-Hydroxy-L-Lysine Delta-Hydroxylysine L-Delta-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproate Hydroxy-Lysine 5-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproic Acid |
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| Definitions |
A hydroxylated amino acid derivative of lysine that arises from post-translational modification. Lysine is converted into 5-hydroxylysine by lysyl hydroxylase, an oxoenzyme that catalyzes the hydroxylation of carbon-5 in lysyl residues found in proteins or peptides. Hydroxylysine residues are required for the formation and stability of triple helical collagen fibrils. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118878 |
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| CAS_Registry |
1190-94-9
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|
| code |
C118878
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
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| Contributing_Source |
CTRP FDA
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| DEFINITION |
A hydroxylated amino acid derivative of lysine that arises from post-translational modification. Lysine is converted into 5-hydroxylysine by lysyl hydroxylase, an oxoenzyme that catalyzes the hydroxylation of carbon-5 in lysyl residues found in proteins or peptides. Hydroxylysine residues are required for the formation and stability of triple helical collagen fibrils.
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| Display_Name |
5-Hydroxylysine
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| FDA_UNII_Code |
2GQB349IUB
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| FULL_SYN |
5-Hydroxy-Lysine (2S,5R)-5-Hydroxylysine L-Hydroxylysine Hydroxylysine HYDROXYLYSINE (2S,5R)-2,6-Diamino-5-Hydroxyhexanoic Acid (2S,5R)-2,6-Diamino-5-Hydroxyhexanoate Erythro-5-Hydroxy-L-Lysine Delta-Hydroxylysine L-Delta-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproate Hydroxy-Lysine 5-Hydroxylysine Alpha,Epsilon-Diamino-Delta-Hydroxycaproic Acid
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|
| label |
5-Hydroxylysine
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|
| Preferred_Name |
5-Hydroxylysine
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| prefixIRI |
Thesaurus:C118878
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| Semantic_Type |
Amino Acid, Peptide, or Protein
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| UMLS_CUI |
C4048291
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| subClassOf |
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