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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Pro-Opiomelanocortin | |
| Synonyms |
Opiomelanocortin Prepropeptide Pro-Opiomelanocortin Proopiomelanocortin Proopiomelanocortin Preproprotein Corticotropin-Lipotropin POMC |
|
| Definitions |
Pro-opiomelanocortin (267 aa, ~29 kDa) is encoded by the human POMC gene. This protein plays a role in peptide hormone-dependent signaling. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C114796 |
|
| code |
C114796
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
Pro-opiomelanocortin (267 aa, ~29 kDa) is encoded by the human POMC gene. This protein plays a role in peptide hormone-dependent signaling.
|
|
| DesignNote |
Pro-opiomelanocortin is cleaved into several biologically active peptides including: NPP, melanotropin gamma (Gamma-MSH), corticotropin (adrenocorticotropic hormone; ACTH), melanotropin alpha (Alpha-MSH), corticotropin-like intermediary peptide (CLIP), lipotropin beta (Beta-LPH), lipotropin gamma (Gamma-LPH), melanotropin beta (Beta-MSH), beta-endorphin and Met-enkephalin. (UniProt)
|
|
| Display_Name |
Pro-Opiomelanocortin
|
|
| FULL_SYN |
Opiomelanocortin Prepropeptide Pro-Opiomelanocortin Proopiomelanocortin Proopiomelanocortin Preproprotein Corticotropin-Lipotropin POMC
|
|
| label |
Pro-Opiomelanocortin
|
|
| OMIM_Number |
176830
|
|
| Preferred_Name |
Pro-Opiomelanocortin
|
|
| prefixIRI |
Thesaurus:C114796
|
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Hormone
|
|
| Swiss_Prot |
P01189
|
|
| UMLS_CUI |
C0033195
|
|
| subClassOf |
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