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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Glycyrrhizin | |
| Synonyms |
Dipotassium Glycyrrhizate Glycyrrhizin Glycyrrhizic Acid (3beta,20beta)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic Acid GLYCYRRHIZIN |
|
| Definitions |
A saponin-like compound that provides the main sweet flavor for Glycyrrhiza glabra (licorice), with potential immunomodulating, anti-inflammatory, hepato- and neuro-protective, and antineoplastic activities. Glycyrrhizin modulates certain enzymes involved in inflammation and oxidative stress, and downregulates certain pro-inflammatory mediators, thereby protecting against inflammation- and reactive oxygen species (ROS)-induced damage. Glycerrhizin may also suppress the growth of susceptible tumor cells. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1117 |
|
| CAS_Registry |
1405-86-3
|
|
| CHEBI_ID |
CHEBI:15939
|
|
| Chemical_Formula |
C42H62O16
|
|
| code |
C1117
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A saponin-like compound that provides the main sweet flavor for Glycyrrhiza glabra (licorice), with potential immunomodulating, anti-inflammatory, hepato- and neuro-protective, and antineoplastic activities. Glycyrrhizin modulates certain enzymes involved in inflammation and oxidative stress, and downregulates certain pro-inflammatory mediators, thereby protecting against inflammation- and reactive oxygen species (ROS)-induced damage. Glycerrhizin may also suppress the growth of susceptible tumor cells.
|
|
| FDA_UNII_Code |
6FO62043WK
|
|
| FULL_SYN |
Dipotassium Glycyrrhizate Glycyrrhizin Glycyrrhizic Acid (3beta,20beta)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic Acid GLYCYRRHIZIN
|
|
| label |
Glycyrrhizin
|
|
| Legacy Concept Name |
Glycyrrhizin
|
|
| NSC Number |
167409 234419
|
|
| Preferred_Name |
Glycyrrhizin
|
|
| prefixIRI |
Thesaurus:C1117
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0061751
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|
| subClassOf |
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