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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Gallium Nitrate | |
| Synonyms |
Gallium Nitrate Gallium nitrate gallium nitrate GALLIUM NITRATE GaN Ganite WR-135675 |
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| Definitions |
A hydrated nitrate salt of the group IIIa element gallium with potential use in the treatment of malignancy-associated hypercalcemia. Gallium nitrate localizes preferentially to areas of bone resorption and remodeling and inhibits osteoclast-mediated resorption by enhancing hydroxyapatite crystallization and reduction of bone mineral solubility. This agent also increases calcium and phosphorous deposition into bone and may increase collagen synthesis. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1109 |
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| ALT_DEFINITION |
A drug that lowers blood calcium. Used as treatment for hypercalcemia (too much calcium in the blood) and for cancer that has spread to the bone (bone metastases).
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| CAS_Registry |
135886-70-3
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|
| Chemical_Formula |
Ga.3NO3.9H2O
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|
| code |
C1109
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| Concept_In_Subset | ||
| Contributing_Source |
FDA
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|
| DEFINITION |
A hydrated nitrate salt of the group IIIa element gallium with potential use in the treatment of malignancy-associated hypercalcemia. Gallium nitrate localizes preferentially to areas of bone resorption and remodeling and inhibits osteoclast-mediated resorption by enhancing hydroxyapatite crystallization and reduction of bone mineral solubility. This agent also increases calcium and phosphorous deposition into bone and may increase collagen synthesis. (NCI04)
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|
| FDA_UNII_Code |
VRA0C6810N
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|
| FULL_SYN |
Gallium Nitrate Gallium nitrate gallium nitrate GALLIUM NITRATE GaN Ganite WR-135675
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|
| label |
Gallium Nitrate
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|
| Legacy Concept Name |
Gallium_Nitrate
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| NCI_Drug_Dictionary_ID |
39249
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|
| NSC Number |
15200
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|
| PDQ_Closed_Trial_Search_ID |
39249
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|
| PDQ_Open_Trial_Search_ID |
39249
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|
| Preferred_Name |
Gallium Nitrate
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|
| prefixIRI |
Thesaurus:C1109
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|
| Semantic_Type |
Pharmacologic Substance Inorganic Chemical
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| UMLS_CUI |
C0061008
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| subClassOf |
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