National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Glucuronidase Inhibitor
Synonyms

beta-Glucuronidase Inhibitors

beta-D-Glucuronidase Inhibitors

Glucuronidase Inhibitor
Definitions

Any substance that inhibits glucuronidase, an enzyme involved in the hydrolysis of glucuronic acid from glucuronides. One of the key processes by which the human body eliminates toxic chemicals and hormones is by glucuronidation. When beta-glucuronidase deconjugates these glucuronides, it prolongs the stay of the hormone or toxic chemical in the body. Inhibition of glucuronidase can produce chemoprotective effects.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1017
code

C1017
DEFINITION

Any substance that inhibits glucuronidase, an enzyme involved in the hydrolysis of glucuronic acid from glucuronides. One of the key processes by which the human body eliminates toxic chemicals and hormones is by glucuronidation. When beta-glucuronidase deconjugates these glucuronides, it prolongs the stay of the hormone or toxic chemical in the body. Inhibition of glucuronidase can produce chemoprotective effects.
FULL_SYN

beta-Glucuronidase Inhibitors

beta-D-Glucuronidase Inhibitors

Glucuronidase Inhibitor
label

Glucuronidase Inhibitor
Legacy Concept Name

Glucuronidase_Inhibitor
Preferred_Name

Glucuronidase Inhibitor
prefixIRI

Thesaurus:C1017
Semantic_Type

Chemical Viewed Functionally
UMLS_CUI

C0053444
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471
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