National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101256
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101256
Preferred Name

Glycoprotein IIb/IIIa Antagonist

Definitions
A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the activation of the platelet-surface integrin glycoprotein IIb/IIIa, thus preventing the binding of fibrinogen and von Willebrand factor leading to the inhibition of platelet activation and aggregation.
Synonyms
Glycoprotein IIb/IIIa Antagonist
Type http://www.w3.org/2002/07/owl#Class
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