loading...| Preferred Name |
Glycoprotein IIb/IIIa Antagonist |
|
| Synonyms |
Glycoprotein IIb/IIIa Antagonist |
|
| Definitions |
A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the activation of the platelet-surface integrin glycoprotein IIb/IIIa, thus preventing the binding of fibrinogen and von Willebrand factor leading to the inhibition of platelet activation and aggregation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101256 |
|
| code |
C101256 |
|
| DEFINITION |
A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the activation of the platelet-surface integrin glycoprotein IIb/IIIa, thus preventing the binding of fibrinogen and von Willebrand factor leading to the inhibition of platelet activation and aggregation. |
|
| FULL_SYN |
Glycoprotein IIb/IIIa Antagonist |
|
| label |
Glycoprotein IIb/IIIa Antagonist |
|
| Preferred_Name |
Glycoprotein IIb/IIIa Antagonist |
|
| prefixIRI |
Thesaurus:C101256 |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C3640054 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02155 | MIO | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C101256 | BERO | LOOM |