National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Total Colonic Aganglionosis

Synonyms

Total Colonic Aganglionosis

TCA

Definitions

The severe form of Hirschsprung disease, this is characterized by a complete lack of nerve cells in the large intestine, and often a partial lack in the small intestine. The bowel is not stimulated without innervation and obstruction ensues. Surgical intervention is necessary.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101040

code

C101040

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99147

Contributing_Source

NICHD

DEFINITION

The severe form of Hirschsprung disease, this is characterized by a complete lack of nerve cells in the large intestine, and often a partial lack in the small intestine. The bowel is not stimulated without innervation and obstruction ensues. Surgical intervention is necessary.

FULL_SYN

Total Colonic Aganglionosis

TCA

label

Total Colonic Aganglionosis

Preferred_Name

Total Colonic Aganglionosis

prefixIRI

Thesaurus:C101040

Semantic_Type

Disease or Syndrome

UMLS_CUI

C0085758

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C101074

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