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Multiple sclerosis ontology
Last uploaded:
November 11, 2014
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| Id | http://scai.fraunhofer.de/MSOntology#BCL2
http://scai.fraunhofer.de/MSOntology#BCL2
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|---|---|
| Preferred Name | BCL2 |
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | BCL2
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| Reference |
Uniprot ID: P10415
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| Context | Gene :HS051615
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| isDefinedBy | The gene that encodes proteins that suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability.
A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for BCL2 is found on chromosome 18, and transfer of the BCL2 gene to a different chromosome is seen in many B-cell leukemias and lymphomas. This causes the BCL2 protein to be made in larger amounts, which may keep cancer cells from dying.
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| prefixIRI | MSOntology:BCL2
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| Synonym | Apoptosis regulator Bcl-2
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| subClassOf | |
| type |
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