Mammalian Phenotype Ontology

Last uploaded: June 28, 2024
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Preferred Name

abnormal humoral immune response
Synonyms

humoral immune response dysfunction

antibody-mediated immune response abnormalities

abnormal humoural immune response

humoural immune response dysfunction
Definitions

any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination
ID

http://purl.obolibrary.org/obo/MP_0001800
definition

any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination
has_exact_synonym

humoral immune response dysfunction

antibody-mediated immune response abnormalities

abnormal humoural immune response

humoural immune response dysfunction
has_obo_namespace

MPheno.ontology
id

MP:0001800
label

abnormal humoral immune response
notation

MP:0001800
prefLabel

abnormal humoral immune response
treeView

http://purl.obolibrary.org/obo/MP_0001790
subClassOf

http://purl.obolibrary.org/obo/MP_0001790
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