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Mondo Disease Ontology
| Preferred Name | neoplasm of mature B-cells | |
| Synonyms |
mature B-cell neoplasms mature B-cell lymphocytic neoplasm mature B-cell neoplasm |
|
| Definitions |
A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). Editor note: is a non-hodgkin in ONCOTREE |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0004949 |
|
| comment |
Editor note: is a non-hodgkin in ONCOTREE
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|
| database_cross_reference |
DOID:706 SCTID:269476000 EFO:0000096 ICD9:202.0 NCIT:C3457 MEDGEN:235305 NCIT:C27910 UMLS:C1334633 ONCOTREE:MBN
|
|
| definition |
A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
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|
| has_exact_synonym |
mature B-cell lymphocytic neoplasm mature B-cell neoplasm
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|
| has_related_synonym |
mature B-cell neoplasms
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|
| id |
MONDO:0004949
|
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-simple#otar |
|
| label |
neoplasm of mature B-cells
|
|
| notation |
MONDO:0004949
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|
| prefLabel |
neoplasm of mature B-cells
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|
| skos_exactMatch |
http://identifiers.org/medgen/235305 http://linkedlifedata.com/resource/umls/id/C1334633 http://purl.obolibrary.org/obo/EFO_0000096 http://purl.obolibrary.org/obo/NCIT_C27910 |
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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| Mapping To | Ontology | Source |
|---|---|---|
| http://purl.obolibrary.org/obo/MONDO_0004949 | OBA | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0004949 | DOVES | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0004949 | KTAO | SAME_URI |
| http://purl.obolibrary.org/obo/MONDO_0004949 | OBA | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0004949 | DOVES | LOOM |
| http://purl.obolibrary.org/obo/MONDO_0004949 | KTAO | LOOM |
| http://www.ebi.ac.uk/efo/EFO_0000096 | CCONT | LOOM |
| http://www.ebi.ac.uk/efo/EFO_0000096 | EFO | LOOM |