loading...| Preferred Name |
dobutamine |
|
| Synonyms |
rac-dobutamine 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol DL-dobutamine dobutaminum racemic-dobutamine dobutamin dobutamina |
|
| Definitions |
A synthetic catecholamine with sympathomimetic activity. Dobutamine is a direct-acting inotropic agent and an adrenergic agonist that stimulates primarily the beta-1 adrenoceptor, with lesser effect on beta-2 or alpha receptors. Via beta-1 adrenoceptor of the heart, this agent induces positive inotropic effect with minimal changes in chronotropic activities or systemic vascular resistance. Dobutamine also causes vasodilation by stimulating beta-2 adrenergic receptors in blood vessels, augmented by reflex vasoconstriction resulting in increased cardiac output. [url:http://purl.obolibrary.org/obo/NCIT_C61733] |
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| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02870 |
|
| definition |
A synthetic catecholamine with sympathomimetic activity. Dobutamine is a direct-acting inotropic agent and an adrenergic agonist that stimulates primarily the beta-1 adrenoceptor, with lesser effect on beta-2 or alpha receptors. Via beta-1 adrenoceptor of the heart, this agent induces positive inotropic effect with minimal changes in chronotropic activities or systemic vascular resistance. Dobutamine also causes vasodilation by stimulating beta-2 adrenergic receptors in blood vessels, augmented by reflex vasoconstriction resulting in increased cardiac output. [url:http://purl.obolibrary.org/obo/NCIT_C61733] |
|
| label |
dobutamine |
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| MIO_ID |
MIO:02870 |
|
| prefLabel |
dobutamine |
|
| reference |
NCIT:C61733 CHEBI:4670 |
|
| synonyms |
rac-dobutamine 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol DL-dobutamine dobutaminum racemic-dobutamine dobutamin dobutamina |
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| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02649 |