loading...| Preferred Name | carvedilol | |
| Synonyms |
coreg |
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| Definitions |
A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. [url:http://purl.obolibrary.org/obo/NCIT_C28906] |
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| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02869 |
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| definition |
A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. [url:http://purl.obolibrary.org/obo/NCIT_C28906] |
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| label |
carvedilol |
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| MIO_ID |
MIO:02869 |
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| prefLabel |
carvedilol |
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| reference |
UMLS:C0054836 NCIT:C28906 CHEBI:3441 |
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| synonyms |
coreg |
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| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02649 |