Preferred Name | abciximab | |
Synonyms |
chimeric 7E3 fab ReoPro |
|
Definitions |
A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation. [url:http://purl.obolibrary.org/obo/NCIT_C76128] |
|
ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02642 |
|
definition |
A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation. [url:http://purl.obolibrary.org/obo/NCIT_C76128] |
|
label |
abciximab |
|
MIO_ID |
MIO:02642 |
|
prefLabel |
abciximab |
|
reference |
NCIT:C76128 UMLS:C0288672 |
|
synonyms |
chimeric 7E3 fab ReoPro |
|
subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02155 |