Myocardial Infarction Ontology

Last uploaded: February 21, 2023
Preferred Name

cytokine biomarker

Synonyms
Definitions

Macrophages and T lymphocytes (T-cells) are the primary producers of cytokines which may have predominantly pro-inflammatory (inflammation-promoting)(IL-1alpha, IL-1beta, IL-2, IL-6, Il-8, IL-12, TNF-alpha, IFN-gamma) or anti-inflammatory (inflammation-suppressive)(IL-4, IL-5, IL-10, TGF-beta) abilities. Cytokines are small, nonstructural proteins, including interleukins, chemokines, interferons, and tumor necrosis factors, which have a multitude of pleiotropic effects in various organs [1]. They are released in a number of paracrine, autocrine, or endocrine pathways and have been implicated in a variety of infections and immune system-affecting disorders by both proinflammatory and anti-inflammatory mechanisms.[url:http://purl.obolibrary.org/obo/MAXO_0000553]

ID

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02352

comment

Macrophages and T lymphocytes (T-cells) are the primary producers of cytokines which may have predominantly pro-inflammatory (inflammation-promoting)(IL-1alpha, IL-1beta, IL-2, IL-6, Il-8, IL-12, TNF-alpha, IFN-gamma) or anti-inflammatory (inflammation-suppressive)(IL-4, IL-5, IL-10, TGF-beta) abilities. Cytokines are small, nonstructural proteins, including interleukins, chemokines, interferons, and tumor necrosis factors, which have a multitude of pleiotropic effects in various organs [1]. They are released in a number of paracrine, autocrine, or endocrine pathways and have been implicated in a variety of infections and immune system-affecting disorders by both proinflammatory and anti-inflammatory mechanisms.[url:http://purl.obolibrary.org/obo/MAXO_0000553]

label

cytokine biomarker

MIO_ID

MIO:02352

prefLabel

cytokine biomarker

reference

MAXO:0000553

subClassOf

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01324

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