Preferred Name |
cytokine biomarker |
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Synonyms |
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Definitions |
Macrophages and T lymphocytes (T-cells) are the primary producers of cytokines which may have predominantly pro-inflammatory (inflammation-promoting)(IL-1alpha, IL-1beta, IL-2, IL-6, Il-8, IL-12, TNF-alpha, IFN-gamma) or anti-inflammatory (inflammation-suppressive)(IL-4, IL-5, IL-10, TGF-beta) abilities. Cytokines are small, nonstructural proteins, including interleukins, chemokines, interferons, and tumor necrosis factors, which have a multitude of pleiotropic effects in various organs [1]. They are released in a number of paracrine, autocrine, or endocrine pathways and have been implicated in a variety of infections and immune system-affecting disorders by both proinflammatory and anti-inflammatory mechanisms.[url:http://purl.obolibrary.org/obo/MAXO_0000553] |
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ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02352 |
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comment |
Macrophages and T lymphocytes (T-cells) are the primary producers of cytokines which may have predominantly pro-inflammatory (inflammation-promoting)(IL-1alpha, IL-1beta, IL-2, IL-6, Il-8, IL-12, TNF-alpha, IFN-gamma) or anti-inflammatory (inflammation-suppressive)(IL-4, IL-5, IL-10, TGF-beta) abilities. Cytokines are small, nonstructural proteins, including interleukins, chemokines, interferons, and tumor necrosis factors, which have a multitude of pleiotropic effects in various organs [1]. They are released in a number of paracrine, autocrine, or endocrine pathways and have been implicated in a variety of infections and immune system-affecting disorders by both proinflammatory and anti-inflammatory mechanisms.[url:http://purl.obolibrary.org/obo/MAXO_0000553] |
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label |
cytokine biomarker |
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MIO_ID |
MIO:02352 |
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prefLabel |
cytokine biomarker |
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reference |
MAXO:0000553 |
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subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01324 |
Delete | Mapping To | Ontology | Source |
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http://purl.obolibrary.org/obo/OPMI_0000447 | BMONT | LOOM | |
http://purl.obolibrary.org/obo/OPMI_0000447 | PDRO | LOOM | |
http://purl.obolibrary.org/obo/OPMI_0000447 | OPMI | LOOM | |
http://purl.obolibrary.org/obo/OPMI_0000447 | CIDO | LOOM | |
http://purl.obolibrary.org/obo/OPMI_0000447 | KTAO | LOOM |