Myocardial Infarction Ontology

Last uploaded: February 21, 2023
Preferred Name

coagulation factor V

Synonyms

activated protein C cofactor

proaccelerin, labile factor

F5

PTC

factor V

Definitions

Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa. [url:http://purl.obolibrary.org/obo/NCIT_C91335]

ID

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01559

definition

Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa. [url:http://purl.obolibrary.org/obo/NCIT_C91335]

label

coagulation factor V

MIO_ID

MIO:01559

prefLabel

coagulation factor V

reference

NCIT:C91335

synonyms

activated protein C cofactor

proaccelerin, labile factor

F5

PTC

factor V

subClassOf

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00716

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01364

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