Preferred Name |
coagulation factor V |
|
Synonyms |
activated protein C cofactor proaccelerin, labile factor F5 PTC factor V |
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Definitions |
Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa. [url:http://purl.obolibrary.org/obo/NCIT_C91335] |
|
ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01559 |
|
definition |
Coagulation factor V (2224 aa, ~252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade. Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa. [url:http://purl.obolibrary.org/obo/NCIT_C91335] |
|
label |
coagulation factor V |
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MIO_ID |
MIO:01559 |
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prefLabel |
coagulation factor V |
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reference |
NCIT:C91335 |
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synonyms |
activated protein C cofactor proaccelerin, labile factor F5 PTC factor V |
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subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00716 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01364 |