loading...| Preferred Name |
prasugrel |
|
| Synonyms |
effient efient |
|
| Definitions |
An orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. [url:http://purl.obolibrary.org/obo/NCIT_C81566] |
|
| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01072 |
|
| definition |
An orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. [url:http://purl.obolibrary.org/obo/NCIT_C81566] |
|
| label |
prasugrel |
|
| MIO_ID |
MIO:01072 |
|
| prefLabel |
prasugrel |
|
| reference |
NCIT:C81566 |
|
| synonyms |
effient efient |
|
| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02641 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00524 |