Preferred Name |
RID4462 |
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Synonyms |
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ID |
http://radlex.org/RID/RID4462 |
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Definition |
A moderately firm, benign, encapsulated tumor resulting from proliferation of schwann cells and fibroblasts that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of neurofibromatosis 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016) [MeSH] |
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label |
RID4462 |
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May_Cause | ||
Preferred_name |
neurofibroma |
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prefixIRI |
RID:RID4462 |
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prefLabel |
RID4462 |
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Synonym |
neurofibroma (WHO grade I) |
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UMLS_ID |
C0027830 |
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subClassOf |