Molecular Interactions

Last uploaded: August 6, 2024
Preferred Name

tissue distribution
Synonyms
Definitions

Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios. Algorithms have been published to predict the value of this parameter but the quality of the prediction is unknown.

ID

http://purl.obolibrary.org/obo/MI_2120

comment

Algorithms have been published to predict the value of this parameter but the quality of the prediction is unknown.

definition

Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.

has_obo_namespace

PSI-MI

id

MI:2120

in_subset

http://purl.obolibrary.org/obo/mi#Drugable

label

tissue distribution

notation

MI:2120

prefLabel

tissue distribution

treeView

http://purl.obolibrary.org/obo/MI_0640

subClassOf

http://purl.obolibrary.org/obo/MI_0640

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