Molecular Interactions

Last uploaded: June 17, 2024
Preferred Name

transmission electron microscopy

Synonyms

tem

Definitions

Microscopy technique in which a beam of electrons is transmitted through a sample to form an image. Samples can be purified molecules, for which no staining is required in order to detect interaction, or tissue/cells. In the latter case, during the treatment for microscope analysis a tissue section is incubated with high-specificity antibodies coupled to heavy metals (e.g. gold). Any tissue section can then be analysed by electron microscopy to localise the target proteins within the cell. This method supports very high resolution colocalisation of different molecules in a cell.

ID

http://purl.obolibrary.org/obo/MI_0020

definition

Microscopy technique in which a beam of electrons is transmitted through a sample to form an image. Samples can be purified molecules, for which no staining is required in order to detect interaction, or tissue/cells. In the latter case, during the treatment for microscope analysis a tissue section is incubated with high-specificity antibodies coupled to heavy metals (e.g. gold). Any tissue section can then be analysed by electron microscopy to localise the target proteins within the cell. This method supports very high resolution colocalisation of different molecules in a cell.

has_exact_synonym

tem

has_obo_namespace

PSI-MI

id

MI:0020

in_subset

http://purl.obolibrary.org/obo/mi#PSI-MI_slim

label

transmission electron microscopy

notation

MI:0020

prefLabel

transmission electron microscopy

treeView

http://purl.obolibrary.org/obo/MI_0040

subClassOf

http://purl.obolibrary.org/obo/MI_0040

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