Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Nitric Oxide
Synonyms	Nitrogen oxide (NO)
Definitions	A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
ID	http://purl.bioontology.org/ontology/MESH/D009569
altLabel	Nitrogen oxide (NO) Endogenous Nitrate Vasodilator Vasodilator, Endogenous Nitrate Oxide, Nitric Monoxide, Nitrogen Nitric Oxide, Endothelium Derived Endothelium-Derived Nitric Oxide Nitrogen Monoxide Nitrate Vasodilator, Endogenous Nitric Oxide, Endothelium-Derived Monoxide, Mononitrogen Mononitrogen Monoxide
AQL	AA AD AE AG AI AN BI BL CF CH CL CS DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR
cui	C0028128
DC	1
definition	A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
DX	19650101
FX	D000089142 D045462 D020030
HN	1965
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	31C4KY9ESH
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D000089142 http://purl.bioontology.org/ontology/MESH/D020030 http://purl.bioontology.org/ontology/MESH/D045462
isa	http://purl.bioontology.org/ontology/MESH/D018377 http://purl.bioontology.org/ontology/MESH/D016166 http://purl.bioontology.org/ontology/MESH/D045462 http://purl.bioontology.org/ontology/MESH/D001993 http://purl.bioontology.org/ontology/MESH/D064426
Machine permutation	1965
Mapped from	http://purl.bioontology.org/ontology/MESH/C088437 http://purl.bioontology.org/ontology/MESH/C058377 http://purl.bioontology.org/ontology/MESH/C000594696 http://purl.bioontology.org/ontology/MESH/C112653 http://purl.bioontology.org/ontology/MESH/C504137 http://purl.bioontology.org/ontology/MESH/C000634368 http://purl.bioontology.org/ontology/MESH/C498979 http://purl.bioontology.org/ontology/MESH/C544422 http://purl.bioontology.org/ontology/MESH/C110153 http://purl.bioontology.org/ontology/MESH/C110152 http://purl.bioontology.org/ontology/MESH/C093551 http://purl.bioontology.org/ontology/MESH/C000596989 http://purl.bioontology.org/ontology/MESH/C106536
MDA	19990101
MMR	20230226
MN	D01.625.700.500 D01.625.550.500 D01.339.409.500 D01.650.550.587.600 D02.389.508.500
notation	D009569
PA	D064426 D001993 D016166 D018377 D045462
prefLabel	Nitric Oxide
RR	10102-43-9 (Nitric Oxide)
TERMUI	T028508 T046281 T028510 T046285 T028507
TH	NLM (1965) NLM (1999) NLM (1990) FDA SRS (2014) NLM (1994) UNK (19XX) USAN (19XX)
tui	T197 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D009589 http://purl.bioontology.org/ontology/MESH/D026361

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/NDFRT/N0000006603	NDFRT	CUI
http://purl.bioontology.org/ontology/LNC/MTHU047590	LOINC	CUI
http://purl.bioontology.org/ontology/SCTSPA/6710000	SCTSPA	CUI
http://purl.bioontology.org/ontology/VANDF/4021248	VANDF	CUI
http://purl.bioontology.org/ontology/RCD/X799J	RCD	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/409378005	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/CSP/4000-0268	CRISP	CUI
http://purl.bioontology.org/ontology/NDDF/012088	NDDF	CUI
http://purl.bioontology.org/ontology/SNMI/C-10712	SNMI	CUI
http://purl.bioontology.org/ontology/SCTSPA/409378005	SCTSPA	CUI
http://purl.bioontology.org/ontology/RXNORM/7442	RXNORM	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148689	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/6710000	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/LNC/LP173640-6	LOINC	CUI
http://purl.bioontology.org/ontology/MSHFRE/D009569	MSHFRE	CUI
http://purl.bioontology.org/ontology/ATC/R07AX01	ATC	CUI
http://purl.obolibrary.org/obo/CHEBI_16480	ZP	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	FYPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	CHEBI	LOOM
http://purl.obolibrary.org/obo/IDOMAL_0000702	IDOMAL	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01409	MIO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.650.550.587.600	RH-MESH	LOOM
http://scai.fraunhofer.de/MSOntology#Nitric_Oxide	MSO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009569	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C695	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.625.700.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU047590	LOINC	LOOM
http://scai.fraunhofer.de/CSEO#Nitric_Oxide	CSEO	LOOM
http://purl.bioontology.org/ontology/VANDF/4021248	VANDF	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C695	NCIT	LOOM
http://localhost/plosthes.2017-1#2886	PLOSTHES	LOOM
http://purl.bioontology.org/ontology/RCD/X799J	RCD	LOOM
http://www.pepathway.org/peo/1.2#nitric_oxide	PE-O	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Nitric_Oxide	APANEUROCLUSTER	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Nitric_Oxide	APAONTO	LOOM
http://purl.obolibrary.org/obo/OMIT_0010590	OMIT	LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571345044435366052	ACVD_ONTOLOGY	LOOM
http://purl.obolibrary.org/obo/UPa_UPC00533	UPA	LOOM
http://purl.bioontology.org/ontology/CSP/4000-0268	CRISP	LOOM
http://purl.bioontology.org/ontology/NDDF/012088	NDDF	LOOM
http://purl.bioontology.org/ontology/SNMI/C-10712	SNMI	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.339.387	RH-MESH	LOOM
https://go.drugbank.com/drugs/DB00435	MDM	LOOM
http://bmi.utah.edu/ontologies/peontology/C0028128	PE	LOOM
http://purl.obolibrary.org/obo/MESH_D009569	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028128	OCHV	LOOM
http://www.semanticweb.org/ontologies/STO.owl#ede6d1_73cb_4af5_be7b_4fd891d294dd	STO-DRAFT	LOOM
http://www.semanticweb.org/ontologies/STO.owl#ede6d1_73cb_4af5_be7b_4fd891d294dd	CVAO	LOOM
http://purl.bioontology.org/ontology/RXNORM/7442	RXNORM	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148689	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/6710000	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/LNC/LP173640-6	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.625.550.500	RH-MESH	LOOM
http://www.drugbank.ca/drugs/DB00435	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8733	OCHV	LOOM
http://www.projecthalo.com/aura#Nitric-Oxide	AURA	LOOM
http://doe-generated-ontology.com/OntoAD#C0028128	ONTOAD	LOOM
http://www.gamuts.net/entity#nitric_oxide	GAMUTS	LOOM
http://id.nlm.nih.gov/mesh/D009569	MDM	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015428	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	HHEAR	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	HINO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	MCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_16480	ZP	LOOM
http://purl.bioontology.org/ontology/ATC/R07AX01	ATC	LOOM