loading...| Preferred Name |
Abciximab |
|
| Synonyms |
ReoPro |
|
| Definitions |
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000077284 |
|
| altLabel |
ReoPro Chimeric 7E3 Fab CentoRx c7E3 Fab Clotinab Fab, Chimeric 7E3 |
|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PK PO RE TO TU UL UR |
|
| cui |
C0592046 C0288672 C2605669 C0288670 |
|
| DC |
1 |
|
| definition |
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting. |
|
| DX |
20190101 |
|
| HN |
2019 (1994) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 |
|
| Inverse of RB |
X85G7936GV 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2019; ABCIXIMAB was indexed under ANTIBODIES, MONOCLONAL and IMMUNOGLOBULIN FAB FRAGMENTS 1994-2018 |
|
| MDA |
20180709 |
|
| MMR |
20180227 |
|
| MN |
D12.776.377.715.548.114.224.200.125 D12.644.541.500.650.125 D12.776.124.486.485.114.224.060.125 D12.776.124.486.485.680.650.125 D12.776.124.790.651.114.224.060.125 D12.776.377.715.548.680.650.125 D12.776.124.790.651.680.650.125 |
|
| notation |
D000077284 |
|
| PA |
D010975 D000925 |
|
| prefLabel |
Abciximab |
|
| RR |
143653-53-6 (Abciximab) |
|
| TERMUI |
T257710 T257708 T000938715 T257709 T728778 T000938716 |
|
| TH |
US UK NL CA NLM (2008) NLM (2019) NLM (1994) ES USAN (1994) DE AU FR IE |
|
| tui |
T116 T129 T121 |
|
| subClassOf |